Automation, artificial intelligence, geopolitical crises and growing demands in terms of sustainability and social respect are rewriting the rules of work organization. New approaches, new ways of organizing, and different understandings of the relationships between hierarchies are emerging.
Goodbye hierarchy?
Companies are gradually moving away from the classic pyramid model to adopt new organizational structures that can foster better collaboration between business functions, faster decision-making and a stronger sense of worker ownership. Among the most significant evolutions is the horizontal structure, a model characterized by the reduction of hierarchical levels, with a flattening of lines of command and a redistribution of decision-making power within autonomous, multifunctional teams. The goal is to ensure greater operational flexibility, reduce response times to market changes, and foster individual empowerment.
However, the benefits are not without their pitfalls.
The diffusion of responsibilities can lead to lower clarity about individual tasks fostering personal de-emphasis and an increased risk of internal conflicts or operational overlap. For this, it is critical that horizontal organization is supported by sound governance, transparent communication, and structured moments of alignment.
In highly complex environments-such as multinational pharmaceutical companies-the adoption of hybrid models, which combine a traditional overarching structure with “flat” business units within them, could be a particularly effective compromise.
Holacracy, circular governance
One particularly innovative response to the ongoing transformation is the adoption of the Holacracy model, a circular governance system devised by Brian Robertson and adopted by a growing number of companies that focus on agility, transparency, and widespread accountability. Unlike vertical structures or even flat organizations, Holacracy does more than simply eliminate hierarchical levels:it radically redesigns the structure of the enterprise, organizing it as a set of flexible roles and operational circles (the “circles”)that are self-managing according to predetermined rules.
In this logic, people no longer occupy “positions,” but play dynamic roles that can evolve or be redefined according to the needs of the moment. Each circle has decision-making autonomy, but is also an integrated part of a larger system. This model enables rapid response to change, promotes the circulation of information, and enhances individual expertise more directly than traditional systems.
Reskilling
Rising geopolitical tensions and regional conflicts have exposed the fragility of the globalized pharmaceutical supply chain, pushing many companies toward partial reshoring of manufacturing activities, from API synthesis to packaging to quality control. This trend, which had already started in the post-pandemic era, entails a growing demand for production technicians and process engineers, particularly with skills in industrial automation under Industry 4.0. In parallel, the rise of biologic drugs-mRNAs, gene therapies, CAR-Ts-imposes a hybridization of skills between chemistry and biotechnology, making reskilling a central lever for future employability.
Quality control is also affected by a profound transformation: artificial intelligence applied to data analysis and in-line controls complements traditional methods, requiring new digital skills for those aspiring to Qualified Person or QC analyst roles. Change extends to environmental and energy sustainability: low-impact technologies are set to become a standard in European pharmaceutical manufacturing.
Experts from international markets
Internationally, the focus is shifting to new emerging markets, particularly sub-Saharan Africa, where population growth and the need for access to quality medicines are opening up new opportunities. The increasing regulatory autonomy of non-OECD countries is also challenging the dominance of GMP standards and “Western” patents.
In this context, experts in international regulation and local clinical needs analysis will become key figures for industry. In this fluid and challenging scenario, the undergraduate and postgraduate education system will have to evolve rapidly, promoting interdisciplinarity, internationalization and co-design with stakeholders.